Tonya is a 42 year old mother of 4 who has a disease called Alpha 1 Antitrypsin Deficiency. She is in desperate need of prolastin infusions and without them doctors say she only has six months to one year left to live. The insurance has denied the claim to pay for these infusions but this mother has the right to live and needs your help. She will dispute the insurance decision however that could take more time than she has.
Alpha 1-antitrypsin deficiency (α1-antitrypsin deficiency, A1AD) is a genetic disorder that causes defective production of alpha 1-antitrypsin (A1AT), leading to decreased A1AT activity in the blood and lungs, and deposition of excessive abnormal A1AT protein in liver cells. There are several forms and degrees of deficiency, principally depending on whether the sufferer has one or two copies of the affected gene because it is a co-dominant trait. Severe A1AT deficiency causes panacinar emphysema or COPD in adult life in many people with the condition (especially if they are exposed to cigarette smoke), as well as various liver diseases in a minority of children and adults, and occasionally more unusual problems. It is treated by avoidance of damaging inhalants, and in severe cases by intravenous infusions of the A1AT protein or by transplantation of the liver or lungs. It usually produces some degree of disability and reduced life expectancy.
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