In 2014, Megan and JC Leston received life-changing news: their son had been diagnosed with Cri du Chat (5p- syndrome), a rare genetic disorder with a daunting prognosis. Determined to create hope and a better future-not just for their child, but for families everywhere-they founded the Cri du Chat Research Foundation (CDCRF).

What began as a personal journey quickly became a movement. CDCRF is a volunteer-powered nonprofit dedicated to advancing science and supporting families. We focus on funding translational research, building expert networks, and accelerating the development of real treatments for 5p- syndrome.

Cri Du Chat Research Foundation, Inc

Thanks to your generosity in the past, we

were able to begin the Drug Repurposing

Screen for 5p- Syndrome and successfully

complete Part 1. This was a tremendous

milestone — and now, we are ready for the

next step.

Our goal is to raise $150,000 to complete

Part 2 of this vital research. With your

support, we hope to move closer to finding a

treatment — and one day, a cure for the symptoms of 5p-

Syndrome.

Your presence, kindness, and commitment

mean more than words can express.

Together, we can make an impact not only

for Liam but for all families affected by this rare

disease.

With gratitude and hope,

JC & Megan Leston

proud parents of Liam Leston