In 2022, Joe Cade was diagnosed with Adult-Onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia (ALSP)—a rare, rapidly progressive, and ultimately fatal neurological disorder. During the last three years of his life, the disease took away Joe’s ability to work and care for himself, but it never took away his strength, his humor, or his love for those around him.

Joe’s wife of 11 years became his devoted caregiver while continuing to work full-time to manage expenses, including Joe’s group home and medical care. She did this with unwavering love and grace—without complaint, and without hesitation—caring for Joe until his final days.

Joe’s youngest brother, Jeff, was diagnosed with ALSP in 2021, two years after a misdiagnosis of Multiple Sclerosis. The disease attacked his motor skills, leaving him unable to walk or speak clearly. In 2022, Jeff underwent a bone marrow transplant in hopes of halting the disease’s progression. While the transplant stabilized the disease, Jeff continues to require round-the-clock care.

Joe loved his family more than himself. A financial contribution to his wife and brother through this GoFundMe/Memorial Fund page is exactly what Joe would have wanted in lieu of flowers. For those wishing to make a broader impact, we invite you to contribute to the United Leukodystrophy Foundation in Joseph’s honor at ulf.org/donate.

Our family knows we are not alone. We recognize that so many others are facing their own battles—whether with terminal illness, medical costs, or the daily challenges that come with caring for a loved one.

We are profoundly grateful for the outpouring of love and support from family, friends, and the communities of Katy, Texas, Porterville, and Morro Bay, California. Your kindness has carried us through. We will never forget.

With love and gratitude,

Kristy, Janie, Jeff, & Kim