Help 2 year old Esme cure her leukaemia

This is Esme. Esme is 2 years and 7 months old. She loves lions, narwhales and playing hide and seek outside. Right now we have no guarantees she will see her third birthday...

In June 2018 Esme at just 22 months old was diagnosed with high risk acute myeloid leukaemia whilst on holiday.

She spent five months as an in-patient at the Royal Marsden, Sutton and received a stem cell transplant in September after three rounds of intense chemotherapy.

 After six months of steady recovery, in April we heard the news we've dreaded; the leukaemia has returned to Esme's bone marrow.

We have sought the advice of several leading, global consultants that specialise within high risk AML.  They have emphasised heavily that Esme's best chance of cure is a second transplant ASAP. 

We are now fundraising to afford this treatment as in all likelihood it will not be available on the NHS. NHS policy is typically not to offer second transplants to patients who relapse within 12 months, but due to the aggressive nature of her disease, Esme simply may not have that long...

In the US and other private centres, second transplants are offered within one year. For her second transplant the plan would be to use an adult (rather than original umbilical cord) donor and manipulate more 'graft versus host effect' to eradicate the leukaemia - so there is every hope for a permanent cure.

Esme's parents, Will and Rebecca, are desperate to save Esme's life. She is their only child and Rebecca suffered 4 miscarriages (and 3 operations, one which nearly killed her) to bring Esme into the world. Throughout all her treatment Esme has been the epitome of resilience, positivity and cheekiness, and deserves a shot at a permanent cure for life.

To read more of Esme's story, click here  . 

For larger fundraising ideas/ enquiries please contact [email redacted]


PLEASE NOTE:  Due to the fact we will no longer be able to use the funds for transplant we will now be splitting the funds raised between CCLG/AML research and also a legacy foundation to continue Esme's memory - the vision for which will be confirmed in due course. 


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  • Mick & Jo 
    • £5 
    • 1 mo
  • Anonymous 
    • £30 
    • 4 mos
  • Anonymous 
    • £5 
    • 5 mos
  • Anonymous 
    • £10 
    • 5 mos
  • Galyna Rufino 
    • £10 
    • 6 mos
See all

Fundraising team: Team Esme (12)

Will Handley 
Raised £62,033 from 691 donations
London, Greater London, United Kingdom
Rebecca Handley 
Team member
Raised £21,864 from 151 donations
Michael Handley 
Team member
Raised £12,826 from 104 donations
Michael Wadsworth 
Team member
Raised £6,623 from 243 donations
Chloe Brown 
Team member
Raised £4,209 from 76 donations
See all
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