Hey everyone—our incredible community of friends, family, and supporters,

First, I’d like to express my eternal gratitude for standing by us through every twist and turn since Brody's Ewing's Sarcoma diagnosis in August of 2024. Your prayers, messages, and donations have been indispensable during rounds of chemo and proton therapy that let to remission earlier this year. We've poured everything into preventing recurrence by changing to a whole food organic diet, as well as many other changes and naturopathic therapies. He's been battling nerve damage in his right leg from the spine but Brody keeps pushing with his unbreakable spirit.

We have huge news to share—both a win and a setback. Out of respect for Brody's wishes, we stayed silent about this next part until now: In November 2025, he was diagnosed with therapy-related Acute Myeloid Leukemia (AML), a secondary cancer from his earlier treatments, with the t(9;11) KMT2A::MLLT3 translocation, FLT3, and STAG2 mutations. He asked us not to tell anyone while he processed it and fought through, and we honored that. The big victory? We've beaten the AML! After starting the Augment 102 regimen (FLA backbone with fludarabine, cytarabine, idarubicin, plus/minus GCSF and ongoing Revumenib), his blood tests showed 0% blasts in just two days. Upon completion of treatment for AML, his marrow showed zero evidence of Leukemia, which was a better than expected result. Unfortunately, during the process and due to his low white blood cell counts he developed a fungal infection. Once they identified the fungal infection, it responded very quickly to Ambisome and has gotten much better.

Now the bad news, new scans and a biopsy have confirmed that the original Ewing's Sarcoma is back. It's hard to digest after thinking we were in the clear, but we're catching it now and gearing up to fight again. This means more treatments ahead, and we’re not sure what that looks like. We’ve been advised to bring him home as our doctor isn’t sure that his body is up for another round of chemotherapy and the Ewing’s appears to be pervasive at this point.

Between the time that I originally wrote the paragraph above and when I'm sending it out, this has evolved significantly. Brody says he doesn't want to give up and wants to continue to fight. We also got a small piece of what appears to be good news. We had them biopsy some of the lesions in his back and his arm that lit up on the PET scan, but I was skeptical that they were actually Ewing's because of how quickly they showed up on the body and that they appeared to be resolving. The initial biopsy of these lesions didn't appear to be Ewing's. There were no small blue cells and rather than a fibrous mass, it was a mucous like structure. We're waiting for the final pathology reports, but that is a good sign that it's not as pervasive as the doctor thought on the PET scan.

The end game for the AML was to get to bone marrow transplant. We considered ourselves fortunate that Abby is an exact match to Brody so we had a donor. Unfortunately, the Ewing's precludes us from going to transplant. We have to knock out this cancer before we can get to transplant. The other unfortunate part of not being able to go directly to transplant is that transplant would likely have positive effects fighting the Ewing’s Sarcoma, so if we could just get there and get through it, it could help to solve both cancers. Unfortunately, transplant is a very difficult process and besides needing to kill the Ewing’s and keep the AML at bay, transplant has significant risks on it’s own.

Your support has already covered so much, and now we're asking for help to keep going strong: funding for complementary therapies like hyperbaric oxygen (HBOT) to aid recovery, mebendazole, ivermectin, mistletoe injections to support his system, plus ongoing meds, home healthcare, and managing that neuropathy. Every contribution helps us focus on healing without the financial weight. I’m going to be honest. The odds are very long at this point, but if anyone is able to overcome this it’s Brody. He’s so amazingly tough and strong and his body just keeps fighting.

If you can donate and/or share this update, it would mean everything to us. We'll keep you posted on progress—scans, biopsies, and wins along the way. Brody's got this, and so do we, thanks to you.

With so much love and hope, Dustin, Megan and the Matteson Family

#BStrong #BeatCancerTwice (And Keep Going)