Forever Mei
Donation protected
Jiangmei Yin Ph.D
Smiley angel is on the way to paradise. My forever love
EDUCATION
Ph.D., 2003-2006 Molecular Immunology, China Agricultural University, Beijing, China
M.S., 2000-2003 Genetics and Molecular Biology, Capital Normal University, Beijing,
China.
B.S., 1993-1997 Biology,Hebei Normal University, Shijiazhuang, China.
EXPERIENCE
Resource Techologist 2015.4-
CVPF, Upenn
Research Associate 2011- 2015.1
Dr. Jean D. Boyer lab and Human Immunology Core (HIC), Department of
Pathology and Laboratory Medicine, University of Pennsylvania School of
Medicine, PA, 19104.
Clinical trials and clinical research works focus on the following areas
1) Developing and performing the cellular immunology experiments and analyzing the data for clinical studies.
· Flow cytometry-based assays and analyze the data for different studies. (16-color flow panel to test function of immune cells in HIV chronic infection.)
· Multiplex cytokines/chemokines assays by luminex (more than 50 kits).
· ELISAs for different purpose.
· ELISpot for clinical trials. (247 EILISpot plates for HPV-003 study).
· Tissue culture and blood processing.
· Some molecular immunology technologies.
2) Improving standard operating procedures (SOP) to ensure safety, security, quality, and accuracy of results. For example,
· Modify SOP to ensure safety to run infection samples in luminex machine.
· Improve procedures to isolate the lymphocytes from biopsy samples.
3) Designing and performing new procedures, for example,
· Successfully develop an ELISA kit assay by testing microparticles (CD31, CD41) for diabetic patient.
· Design and test 10-colour and 16-color flow panels in HIV+ patients.
4) Maintaining, calibrating and validating the machines and oversee the quality control processes. Collecting data and organizing the laboratory.
5) Involved almost all of clinical trials in the HIC. For example,
· Cancer clinical trials: HPV-002(Phase I), HPV-003(Phase II),
HealthBanks study
· Infectious disease clinical trials: Flu101 study (Phase I).
Postdoctoral Researcher 2007- 2011
Dr. Jean D. Boyer and Dr. David, B. Weiner lab, Department of Pathology
and Laboratory Medicine, University of Pennsylvania School of Medicine.
Independently completed National Institutes of Health (NIH) project: No. R01-A1-071186.
Involved National Institutes of Health (NIH) project: No. P01-A1-071739 and N01-AI 50010 et al.
The research area is T cell immune and vaccine. Research works focus on the following areas.
1) Enhancing the efficacy of SIV/HIV DNA vaccine:
Designing, cloning and expressing cytokines’ genes to improve HIV vaccine efficacy.
Enhancing the effectiveness of HIV/SIV DNA vaccine by adjuvants RANTES, IL-15 and IL-12, respectively, in non-human primate model. (Published in PloS ONE, Vaccine and Virology.)
Enhancing the effectiveness of HIV/SIV DNA vaccine by new delivery methods—EP.
2) Study the mechanism about how the SHIV DNA vaccine works
Study on sustained protection mechanism against HIV in macaques. (Published in AIDS and Vaccine)
Developing a new non-standard immunological assays to investigate protection mechanism of HIV vaccine. (Published on PLoS ONE). A special and high evaluation about the paper has been published on Faculty of 1000 (“F1000”).
3) Study the effect of infectious disease on HIV/SIV vaccine
Study the effect of malaria infection on SIV DNA vaccine. (Published in the Journal of Infectious Disease).
Study the effect of schistosome infection on HIV DNA vaccine in mouse model. (Published in the Human Vaccine & Immunotherapeutic).
Graduate Research Assistant. 2003-2006
Dr. Bin Wang's Laboratory of Molecular Immunology, State Key
Laboratories for AgroBiotechnology, China Agricultural University.
Beijing, China
The research area is molecular immunology and nuclei acid vaccine.
1) Study on the virulence and nosogenesis of Newcastle disease virus (NDV).
2) Improvement of immunopotency of killed vaccine against NDV by a new adjuvant,
modified LMS+ (published in Viral Immunology).
3) Developed a new DNA vaccine against NDV.
4) Enhance protection against Newcastle disease virus by immunized a DNA vaccine
with adjuvants: IFN-γand LMS+ (published in Viral Immunology).
5) Improvement of immunopotency of DNA vaccine by DNA prime-viral protein
boost vaccinations.
6) Study the mechanism of immunosuppression induced by co-immunization with
DNA- and protein-based vaccines against FMDV and NDV.
Graduate Research Assistant 2000-2003
Key laboratory of Genetics and Molecular biology, College of Life Sciences,
Capital Normal University, Beijing, China
Research works focus on the following areas:
1) Fluorescence in situ hybridization experiments showed Localization of RNA polymerase III transcription in the nucleolus not in the nucleoplasm by confocal microscopy.
2) Electron microscope results showed that ultrastructure of the nucleolus and the location of rDNA replicating in root-tip meristematic cells of Triticum aestivum L.
3) Improved the cell transfection with different methods: electroporation and Liposomes.
Smiley angel is on the way to paradise. My forever love
EDUCATION
Ph.D., 2003-2006 Molecular Immunology, China Agricultural University, Beijing, China
M.S., 2000-2003 Genetics and Molecular Biology, Capital Normal University, Beijing,
China.
B.S., 1993-1997 Biology,Hebei Normal University, Shijiazhuang, China.
EXPERIENCE
Resource Techologist 2015.4-
CVPF, Upenn
Research Associate 2011- 2015.1
Dr. Jean D. Boyer lab and Human Immunology Core (HIC), Department of
Pathology and Laboratory Medicine, University of Pennsylvania School of
Medicine, PA, 19104.
Clinical trials and clinical research works focus on the following areas
1) Developing and performing the cellular immunology experiments and analyzing the data for clinical studies.
· Flow cytometry-based assays and analyze the data for different studies. (16-color flow panel to test function of immune cells in HIV chronic infection.)
· Multiplex cytokines/chemokines assays by luminex (more than 50 kits).
· ELISAs for different purpose.
· ELISpot for clinical trials. (247 EILISpot plates for HPV-003 study).
· Tissue culture and blood processing.
· Some molecular immunology technologies.
2) Improving standard operating procedures (SOP) to ensure safety, security, quality, and accuracy of results. For example,
· Modify SOP to ensure safety to run infection samples in luminex machine.
· Improve procedures to isolate the lymphocytes from biopsy samples.
3) Designing and performing new procedures, for example,
· Successfully develop an ELISA kit assay by testing microparticles (CD31, CD41) for diabetic patient.
· Design and test 10-colour and 16-color flow panels in HIV+ patients.
4) Maintaining, calibrating and validating the machines and oversee the quality control processes. Collecting data and organizing the laboratory.
5) Involved almost all of clinical trials in the HIC. For example,
· Cancer clinical trials: HPV-002(Phase I), HPV-003(Phase II),
HealthBanks study
· Infectious disease clinical trials: Flu101 study (Phase I).
Postdoctoral Researcher 2007- 2011
Dr. Jean D. Boyer and Dr. David, B. Weiner lab, Department of Pathology
and Laboratory Medicine, University of Pennsylvania School of Medicine.
Independently completed National Institutes of Health (NIH) project: No. R01-A1-071186.
Involved National Institutes of Health (NIH) project: No. P01-A1-071739 and N01-AI 50010 et al.
The research area is T cell immune and vaccine. Research works focus on the following areas.
1) Enhancing the efficacy of SIV/HIV DNA vaccine:
Designing, cloning and expressing cytokines’ genes to improve HIV vaccine efficacy.
Enhancing the effectiveness of HIV/SIV DNA vaccine by adjuvants RANTES, IL-15 and IL-12, respectively, in non-human primate model. (Published in PloS ONE, Vaccine and Virology.)
Enhancing the effectiveness of HIV/SIV DNA vaccine by new delivery methods—EP.
2) Study the mechanism about how the SHIV DNA vaccine works
Study on sustained protection mechanism against HIV in macaques. (Published in AIDS and Vaccine)
Developing a new non-standard immunological assays to investigate protection mechanism of HIV vaccine. (Published on PLoS ONE). A special and high evaluation about the paper has been published on Faculty of 1000 (“F1000”).
3) Study the effect of infectious disease on HIV/SIV vaccine
Study the effect of malaria infection on SIV DNA vaccine. (Published in the Journal of Infectious Disease).
Study the effect of schistosome infection on HIV DNA vaccine in mouse model. (Published in the Human Vaccine & Immunotherapeutic).
Graduate Research Assistant. 2003-2006
Dr. Bin Wang's Laboratory of Molecular Immunology, State Key
Laboratories for AgroBiotechnology, China Agricultural University.
Beijing, China
The research area is molecular immunology and nuclei acid vaccine.
1) Study on the virulence and nosogenesis of Newcastle disease virus (NDV).
2) Improvement of immunopotency of killed vaccine against NDV by a new adjuvant,
modified LMS+ (published in Viral Immunology).
3) Developed a new DNA vaccine against NDV.
4) Enhance protection against Newcastle disease virus by immunized a DNA vaccine
with adjuvants: IFN-γand LMS+ (published in Viral Immunology).
5) Improvement of immunopotency of DNA vaccine by DNA prime-viral protein
boost vaccinations.
6) Study the mechanism of immunosuppression induced by co-immunization with
DNA- and protein-based vaccines against FMDV and NDV.
Graduate Research Assistant 2000-2003
Key laboratory of Genetics and Molecular biology, College of Life Sciences,
Capital Normal University, Beijing, China
Research works focus on the following areas:
1) Fluorescence in situ hybridization experiments showed Localization of RNA polymerase III transcription in the nucleolus not in the nucleoplasm by confocal microscopy.
2) Electron microscope results showed that ultrastructure of the nucleolus and the location of rDNA replicating in root-tip meristematic cells of Triticum aestivum L.
3) Improved the cell transfection with different methods: electroporation and Liposomes.
Organizer
Xiaoquan Zhang
Organizer
Drexel Hill, PA
