Leeds Marathon 2023

In August 2021, our colleague and friend Simone Taylor sadly passed away from triple-negative breast cancer at the age of 32. Simone was BRCA1 positive, and it is estimated that 1 in 40 women of Ashkenazi Jewish heritage is BRCA+ making them 10 times as likely to carry a BRAC mutation as someone in the general population. This raised her lifetime risk of developing breast cancer from a 12% to 72%.

Raising money to support cancer charities was a cause very close to Simone’s heart. Triple-negative breast cancer is a particularly aggressive and devastating form of the disease, which mostly occurs in women under 50. Around 70% of breast cancers diagnosed in people with an inherited BRCA mutation, particularly BRCA1, are triple-negative. There are fewer targeted treatments for the disease and approximately 46% of TNBC patients will go on to develop distant metastasis. More research is desperately needed to develop new drugs and treatments for TNBC specifically.

Do you want to join me in making a difference? I'm raising money in aid of Yorkshire Cancer Research and every donation will help. Thank you in advance for your contribution to this

cause.

More information about Yorkshire Cancer Research: Yorkshire Cancer Research funds lifesaving research to improve the prevention of cancer, ensure people receive the earliest possible diagnosis and bring the very best treatments to our region.

Thanks to our incredible supporters, we've been reducing the impact of cancer in Yorkshire for nearly 100 years.

We tackle local cancer issues to ensure everyone has the very best chance of living a long and healthy life.