Donations for Mikey [Fanconi Anemia]
Donation protected
My cousin, Mikey, is 3 years old & has been diagnosed with Fanconi Anemia, an extremely rare bone marrow disease that affects 1 in 160,000 people worldwide!! The testing is very expensive, and once a donor is found, Mikey and his family will have to stay out of state for 3 months while he gets treatment. It is super important that our family gets help to test any possible bone marrow donor!! Please help us help Mikey!
WHAT IS FANCONI ANEMIA?
Fanconi anemia (FA) is one of the inherited anemias that leads to bone marrow failure (aplastic anemia). It is primarily a recessive disorder: if both parents carry a defect (mutation) in the same FA gene, each of their children has a 25% chance of inheriting the defective gene from both parents. When this happens, the child will have FA. Scientists have now discovered 16 FA or FA-like genes. These genes account for over 95% of all known FA patients. Some patients do not appear to have mutations in these 15 genes, so we anticipate that additional FA genes will be discovered in the future.
FA occurs equally in males and females. It is found in all ethnic groups. The current median lifespan for a patient with FA is 29 years, although there are now patients living into their 30s, 40s and 50s. Though considered primarily a blood disease, it can affect all systems of the body. Many patients eventually develop acute myeloid leukemia (AML) at a very early age. FA patients are extremely likely to develop a variety of cancers and at a much earlier age than patients in the general population. Patients who have had a successful bone marrow transplant and are therefore cured of the blood problem associated with FA still must have regular examinations to watch for signs of cancer.
WHAT IS FANCONI ANEMIA?
Fanconi anemia (FA) is one of the inherited anemias that leads to bone marrow failure (aplastic anemia). It is primarily a recessive disorder: if both parents carry a defect (mutation) in the same FA gene, each of their children has a 25% chance of inheriting the defective gene from both parents. When this happens, the child will have FA. Scientists have now discovered 16 FA or FA-like genes. These genes account for over 95% of all known FA patients. Some patients do not appear to have mutations in these 15 genes, so we anticipate that additional FA genes will be discovered in the future.
FA occurs equally in males and females. It is found in all ethnic groups. The current median lifespan for a patient with FA is 29 years, although there are now patients living into their 30s, 40s and 50s. Though considered primarily a blood disease, it can affect all systems of the body. Many patients eventually develop acute myeloid leukemia (AML) at a very early age. FA patients are extremely likely to develop a variety of cancers and at a much earlier age than patients in the general population. Patients who have had a successful bone marrow transplant and are therefore cured of the blood problem associated with FA still must have regular examinations to watch for signs of cancer.
Organizer
Matthew Ansline
Organizer
