<div>In August 2021, our beautiful baby Ness died at 38 weeks of pregnancy and was born a few days later. Her absence is felt so keenly in our lives and the lives of our wider family. We love her and miss her always. Her life was short, but she continues to touch the lives of many and in this way, we find ways to remember her.
</div>
<div><br />
</div>
<div>We believe Ness would have been a force for good in the world and even though we would always have wished for her to be here above all, we feel honoured and inspired to commit to furthering her legacy through The Ness Fund.
</div>
<div><br />
</div>
<div>Our aims are:
</div>
<div><br />
</div>
<div>To increase research and understanding of stillbirth, so that fewer families face the heartbreak of saying goodbye to their baby;
</div>
<div><br />
</div>
<div>To support education and awareness of baby loss so parents can make better and more informed decisions about when to seek help;
</div>
<div><br />
</div>
<div>To support improved practical and emotional support to bereaved families;
</div>
<div><br />
</div>
<div>To promote our environment and natural world, as this is where we find and love Ness now.
</div>
<div><br />
</div>
<div>The only found cause for Ness's death was a placenta disorder known as Delayed Villous Maturation. There is emerging research in this field but there is a lot more to be understood before diagnosis in pregnancy and treatment would be possible. The Ness Fund wishes to support the amazing research being done in this area by the charity Tommy's. The Ness Fund is currently supporting a PhD student, Sharanam Soni, supervised by Professor Alex Heazell of the Tommy's Rainbow Clinic/University of Manchester. Sharanam and Professor Heazell have aspirations to transform the understanding of Delayed Villous Maturation across a three year project. The project aims to produce precise diagnostic criteria for DVM, identify which clinical characteristics are associated with significant DVM, and determine whether factors associated with DVM affect placental vascular development. This research study is now over eight months underway and is making good progress. We recently had the privilege of visiting The Manchester Rainbow Research Centre and heard about the preliminary findings of Sharanam’s extensive review of the research in this field to date, and the next steps of the project. It was wonderful to see how closely the research laboratories and clinical work is organised at the Manchester Rainbow Clinic.
</div>
<div><br />
</div>
<div>***CHRISTMAS 2024***
</div>
<div>The Ness Fund Christmas Appeal 2024
</div>
<div>Spatial RNA Sequencing
</div>
<div><br />
</div>
<div>As our supporters know The Ness Fund is currently funding a research PhD into Delayed Villous Maturation, the placenta disorder that was the most likely cause of Ness’s death. This year has been a special one with PhD student Sharanam Soni and supervisor Professor Alex Heazell working hard on the project. Sharanam’s review of the literature was published and there were many insights into how we can understand DVM better. The team have also written an information sheet on DVM published by Tommy’s. 
</div>
<div><br />
</div>
<div>Next year, there are big plans for the research. Prof Alex and Sharanam have told us that spatial RNA sequencing will be a technique used for the bulk of the work. It is a technique that shows exactly what individual cells are expressing and how they map to different pathways.
</div>
<div><br />
</div>
<div>Sharanam has told us a bit more about this technique and its relevance to the research on Delayed Villous Maturation. 
</div>
<div><br />
</div>
<div>‘Spatial RNA sequencing is a cutting edge technology that helps to visualise exactly which cells in the placenta have altered RNA expression. This will give us access to a large amount of novel data about DVM placentas and how they vary from healthy placentas. Further analysis may also give us more information on factors that contribute to the development of DVM.’
</div>
<div><br />
</div>
<div>The issue is this highly specialist technique is expensive, about £5000 for four samples. 
</div>
<div><br />
</div>
<div>This is groundbreaking research that you can help us fund. Every little helps. If you’d like to remember Ness and other precious babies with us this Christmas and contribute to further detail and maternal health research, please consider making a donation via the link in our bio. Thank you so much for following the research developments and supporting us. 
</div>
<div>***
</div>
<div><br />
</div>
<div>The Ness Fund has also supported smaller projects, including providing funds for Kicks Count Charity to have a stall at the Baby Show in London. As well as research, we believe in supporting essential information and education that allows parents to be fully informed and empowered to make choices about their baby’s care in utero.
</div>
<div><br />
</div>
<div>Alongside our ongoing commitment to Tommy's and the research they are undertaking, we are looking for other projects to support our aims and to be the force for good in the world that Ness would have been had she lived.
</div>
<div><br />
</div>
<div>Thank you so much for donating to The Ness Fund so we can continue to support projects such as these in the future.
</div>
<div><br />
</div>
<div><em>The Ness Fund operates as a restricted charitable fund under the registered charity Princes Exchange Foundation. Your donation will solely go to The Ness Fund and not other funds under the Princes Exchange Foundation. </em>
</div>

CK AND THE DRAWING BOARD

Anonymous

Clare Tierney-Kitchener

ANDREW RALPH FAWKES

Kim Hope

Helen Morris

Annie Vinted Sales

Cash sales keyrings Connell

Annie Cash sales of wooden items

Amy Devlin

Ellie Mitchell

Cecilia Hue

Stefanie Moriarty

Holly Machemedze

Geoff Peppiatt

Fergus Bisset

The Ness Fund

platform

Platform is iOS

Android

Adyen Google Pay Development Audience

$opt_dummy_attribute

English only

Deprecate Stripe Legacy

dyn_template_ids

Adyen V6 Bene Transfer & MyMoney Campaign Organizers - test01

Bene transfer V6 and AdyenV6MyMoney Campaign Organizers - production

OneTrust next-app audience

fundCountryCode

NextDoor Share Option Users

Fundraisers with Reactions feature capability

fundCurrencyCode

US + Non-charity COs Only

locale

fund country is US and user language is English

personId

comms-internal-person-ids

Enhanced Story Experience Users

Suggested Goal Experience Users

user language is English and fund country: US, AU, DK, FI, IE, NO, SE, CA, GB; 

Poster share - new funds eligible (newest 9/18)

Streaming widgets beta user

paymentProcessor

3DS payment method

user language is English and fundCountry: US, AU, DK, FI, IE, NO, SE, CA, GB; 

currencyCode

Money Box Donation List Prompt Experiment Audience

GoFundMe Employees

ipAddress

Mark Rieth IP Address

Version 9.2.0 and above

Fund is in English speaking country

desktop

Android v12.11.0 and above

Platform is Android

paymentMethodType

checkoutType

Payment method type group to be vaulted on success

admin pr kit prod

EUR Donation Upsell

Share Text generation Skip Fundraiser

(prod) new funds eligible for amp12 (UGC gallery)

fintrac_cad_idv_form_v2 audience

paymentProcessorAccountId

fallback mode accounts

proCampaignId

p2p legacy startfundraising page

AMP24 New Funds Only PROD (DO NOT MODIFY)

countryCode

charityId

UKCharities

Federated Search Internal Testing

route.pathname community

US Donation Upsell audience 

Auto Thanks Feature Audience

Supporter Comments Eligible Funds

International Only

fundId

braze fundraiser group 

Payment Identity Transfers ATO Risk Check (Targeted) - Production

Fundraiser Saved Payment Method Rate Limit Bypass (Production)

leaderboard-partner-id-audience-givepanel

Version 9.2.1 and above

AUD Donation Upsell audience

fundraiserCountryCode is US/EN

Active Fundraiser - Smart Default Cadence

DAF Internal

Vault on success card payment method

Platform is iOS v11.0.0 and above

Desktop users

Person ids

United States (US) users

allow yuno fundraisers for test

Mexico country code

Posters INTL

NPO Profile Opted-In

iOS at or above 12.4.0

non-US recurring donors

Canada Campaign Owner Group

Fundraiser Without Meta Link

Scheduler payment tester gorup

charityCommunityId

Charities allow to be claimed unclaimed (PRD)

Canada (CA) users

UC Tipping v20250115 International

pymk_production_xplr_fe_team

Android at or above 12.2.0

Profile photo entry point audience

smart goals (fundraiser/manage) on test01

Activity Tracking v1 Beta Testing

start gfm intl allowed locales

Platform is iOS v11.2.0 and above

NPO upsell education category

unclaimed charities

prod_ach_audience

AI Chatbot Audience

amp13 only new funds (prod) (anyword auto)

UC Flow Enabled (Prod)

Payment Identity Beneficiary Verification - Production

shared notification bell audience

Custom users

ach frontend audience

Android v11.0.0 and above

Users Receiving Payments Paused Notifications

smart goals test01

Manage Coach - US English Organizers Only + new funds only

Team EGG - IP Address list

NPO recommendations prod

Fundraiser Without Instagram Deep Link

Native 11.4.0 and above

UC Tipping v20250107

Users Receiving Braze KYC Validation Failed

Native 11.3.0 and above

ai_title_page

anyword

openai

control

manual_entry

userEmail

template_id

userId

fundUrl

isCharityCo

email

appVersion

shouldBucketIntoExperiment

partnerId

donationCadence

isActiveFundraiser

isPartner

isMobile

npoProfileOptIn

fundIsLinkedWithMeta

hasSessionDonation

categoryGroup

isCampaignOwner

fundHasInstagramDeepLink

Native 11.4.0 and higher

New funds eligible - Video Sharing (PROD)

GB Donation Upsell audience 

Auto Thanks V3 Rollout Audience

Thank you V3 testing whitelist

isRecurringFriendly

Is Recurring Friendly

Excluded funds - Video Sharing

NPO upsell animals category

NPO upsell disaster relief category

Logged In Users

CH Donation Upsell audience

Android v10.6.0 and above

NPO upsell essential needs category

NPO upsell medical category

userCurrencyCode

Localized Currency

NPO upsell cancer category

v11.5.0 and above

testAudience

pathname

Survicate

appVersion is at or above 12.8.0

Non-charity fund

isChallengeFundraiser

challenge-fundraisers

Payment Identity Launch Verification - Production

New funds eligible - Posters v2

CAD Donation Upsell Audience

Braze Email Tester

NPO Profile Opted-Out

iOS App Version

hasKnownDonors

PYMK has donors

iOS v12.3.0 and above

Enter your donation forThe Ness Fund