<div>Greetings friends, family and wonderful supporters of “a cur” for Zoey.  
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<div>Zoey is now 12 years old and attending Middle School.  She had a busy summer as she again attended several special needs camps.  She continues to progress well in school and participate in Girl Scouts, challenger baseball, adaptive skiing and adaptive surfing.  She is having more respiratory issues and requires a nurse overnight, but otherwise is doing well.  She is an amazing girl and her smile brightens everyone’s day.  
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<div>Please help us achieve “a cur” for Rett syndrome with a generous donation to our 2026 campaign.  Rett Syndrome Research Trust (RSRT) launched a $40 million Roadmap to Cures in 2024 initiative with a goal to have next generation gene editing and RNA-editing therapies in clinical trial by 2028, which will require increased fund raising.  While RSRT has successfully motivated companies to start gene replacement clinical trials, science has progressed.  The gene replacement therapy is exciting and potentially life changing, but it requires just the right dosage as too little won’t work and too much creates problems.  The gene and RNA-editing therapies offer a potentially complete and more effective cure, which is why RSRT started this campaign.  Recently, an Italian company, Reverta, with RSRT’s help started a Rett program with that will use a new delivery mechanism that, if successful, will provide better coverage in the brain, improved safety and lower cost.
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<div>To support RSRT’s Roadmap to Cures, Bonnie and I have increased our annual donation to $15,000.  We value the wonderful support you have provided, and hope you can continue.  If you can and are willing to increase your support that would be terrific.  Either way we greatly appreciate all you have done to help our Zoey!  If you have any issues or need help donating, please contact us and we will help.
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<div>Rett Syndrome Research Trust (RSRT) accomplishes a lot with limited resources and achieving a cure is their only mission.  YOU ARE MAKING A DIFFERENCE!!  
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<div>There is hope but we need your help to achieve “a cur”.
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<div>Dennis and Bonnie
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<div><strong>Rett Syndrome Research Trust</strong>
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<div><em>We are the organization working to cure Rett Syndrome. As the largest worldwide funder of Rett research, we're advancing genetic medicines that target the root cause of Rett. The gene therapy programs currently in clinical trials were started and incubated at RSRT. We are the go-to partner for genetic medicine scientists and companies. The commitment and passion of Rett families in the US and around the globe make our critical work possible. If you want a cure as urgently as we do, we welcome you to our site and invite you to join us in our quest. With the launch of Roadmap to Cures 2.0, we've set an ambitious goal and need all hands on deck to achieve it. Together we can cure Rett syndrome!</em>
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<div>Every contribution, big or small, makes a real impact. Even just a few dollars can help move this mission forward and reach those who need it most.
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<div>If you can’t donate right now, sharing this fundraiser is also incredibly helpful. Thank you so much for your kindness and generosity. It means the world to me.
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Virginia Edleman

Charles Mackey

"a cur" for Zoey 2026

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"a cur" for Zoey 2026

Mancano ancora $26,950. Aiutaci a creare slancio.