Noah's Fight

Noah’s Fight

The Holmes family has been through so much during the last couple years.  Tim and Megan’s son; Noah was diagnosed with Stage IV high risk neuroblastoma in February 2012. 

We have started a fundraiser to help alleviate the financial burden that this family has had to face.  Any amount of money donated will go to help this family with medical bills not paid by their insurance, to help them keep their family home, help put gas in their car to drive back and forth to endless hospital visits and doctor visits, and help with time lost at work when they have used all their paid time off.  I hope you will find it in your heart to help this family in any way that you can.  Donations can be made at any Fifth Third bank under Noah’s Fight.  We have also opened a P.O. box, so anyone can send cards or well wishes to Noah and his family.  The P.O. Box address is P.O. Box 888 Independence, KY 41051 

Tim and Megan work different shifts in hopes that one of them is always with Noah during this trying time in their lives.  Tim and Megan are extremely grateful for all the help they have received from friends and family along their sometimes endless journey to help their son find his cure for this horrible cancer. 

In February 2012, Tim and Megan Holmes noticed their son; Noah was limping when he walked.  He complained his leg hurt, but they saw no reason, (bruising, bumps, etc) for this pain.  They took Noah to see his pediatrician for an evaluation.  The Dr. did blood work and took an x-ray.  The Dr. also saw no reason for his limp or pain.  After about a week and no relief to his pain or limp, they called the Dr. again and they were referred to an orthopedic doctor.  The orthopedic doctor also did blood work and took an x-ray to compare it to the pediatricians’ x-ray.  The orthopedic doctor noticed cloudiness on the bone in the first x-ray and even more cloudiness in the second one.  He immediately sent Noah to Cincinnati’s Children Hospital for further evaluation.  There Noah received a MRI and bone biopsy.  This is where their nightmare began. 

Noah was only a few months shy of turning 3 years old and was given the horrible diagnosis of Stage IV high risk neuroblastoma.  They had to put Noah in a full body cast due to the biopsy, fracturing his thigh bone.  He was hospitalized for a series of tests and consultations.  Somewhere during this time, Noah was given a central line to help with feedings and medications.

In March 2012 they removed Noah’s adrenal gland (where this type of cancer begins) and then he began an investigational chemotherapy and radiation therapy (MIBG).  During the radiation, Noah was contained to a room, in bed, where his parents were not allowed to even touch him, due to the exposure of the radiation.  Noah was hospitalized off and on from March to July.  In June, scans showed much improvement and no signs of tumors!!  In July he completed his radiation therapy. 

In August 2012, the Make-A-Wish foundation granted Noah’s wish to go to Disney and meet Buzz Lightyear!!  Thank you, Make-A-Wish!!  So, August was a good month for the Holmes’ family.  They were able to take a break from the hospital stays and go to Disney World and have some family fun!!

September 2012, began stem cell/bone marrow transplant which came with a high risk of VOD, (Venous occlusive disease, which in over 30% of cases it is fatal).  So, this was a very emotional time for their family.  During this time, Noah was hospitalized for over a month.

In November 2012, Noah began radiation therapy to his abdomen to target the adrenal gland area.  The radiation therapy was completed December 11th.  And, Noah’s hair began to grow back!!

A new year began with Noah having his central line removed and he began an antibody therapy.  Noah did not tolerate this therapy and it had to be stopped.  Noah’s blood pressure was dropping too low and it was affecting his heart.  They were able to continue an oral therapy of accutane, which has shown to kill the cells of neuroblastoma.  Noah continued this therapy until June 19th, 2013. Soon after this, Noah had more scans done and they showed Noah to be cancer free!!

The Holmes family celebrated the Fourth of July 2013 with a cancer free party for Noah!  Later that month, they were able to vacation with Tim’s father and step mother in Myrtle Beach, SC.  We all celebrated there with beach days, pool days and family adventures.

When they returned from their vacation, it was time again for rescans.  This is when their family received the devastating news that Noah’s cancer had returned in his right femur above his knee.  They immediately began 2 oral chemotherapies and an infusion therapy (all of these therapies are clinical trials and done to maintain the cancer not cure it).  Unfortunately, Noah’s body did not tolerate these therapies as they had hoped and they had to start reducing the doses in November 2013.  He continued this therapy as his body would tolerate it from Sept. 2013 to June 2014, (but he was not able to take the chemo as planned due to platelets being too low, etc).  So, for several months the therapy was given as Noah could tolerate it.  And scans continued to show the cancer progressing. 

August 2014, Noah began another clinical trial therapy of an oral medication, LDK which is suppose to block mutative proteins in Noah’s body.  And again, scans showed no improvement.

September 2014, Noah began another round of radiation therapy along with the chemo.  Noah is now continuing the chemo as his body will tolerate it, but blood tests have to be done and if platelets are low, he has to postpone therapy until his cell counts are at a safe level.  We are praying and still very hopeful that the doctors can find the right therapy for Noah. The financial and emotional burden this family has had to face over the last couple years is growing.  All donations, prayers, well wishes, etc are so much appreciated!!  Let’s rally together for this family and bring them some love and relief!!  Thank you all, in advance, for your love and support!!


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Laurie Crider Holmes 
Grandville, MI
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