<div>This is Florence’s official fundraising campaign in partnership with <strong>The</strong> <strong>Azaylia</strong> <strong>Foundation</strong>, who we are incredibly grateful to be supported by.
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<div>The Azaylia Foundation is a registered charity dedicated to supporting children and families affected by childhood cancer. By donating through this page, you are supporting Florence’s fight through a registered charity, with all funds raised going towards helping her access treatment.
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<div>Our daughter, Florence Wilde, turns three in October. Shortly after her first birthday, in November 2024, after weeks of being told her symptoms were due to severe constipation, Florence was found to have a 30cm tumour in her abdomen, alongside disease in her spine. She was diagnosed with high-risk MYCN-amplified neuroblastoma, a rare and aggressive childhood cancer. Overnight, our world changed forever.
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<div>Over the following 18 months, Florence underwent intensive treatment at Birmingham Children’s Hospital, including eight cycles of induction chemotherapy, a 12-hour surgery to remove her abdominal tumour, two stem cell transplants, two cycles of high-dose chemotherapy, radiotherapy and immunotherapy. She spent almost 300 days in hospital and, at times, became so critically unwell that she required intensive care and ventilation.
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<div>Yet throughout every stage of treatment, Florence continued to smile, surprise us and show a strength like no other. We are so incredibly proud of our brave girl.
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<div>In April 2026, Florence completed her frontline NHS treatment. We are incredibly thankful that her end-of-treatment scans are stable and that she is now at home, thriving and enjoying life as the happy, cheeky little girl she has fought so hard to be.
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<div>However, for children diagnosed with high-risk neuroblastoma, completing frontline treatment doesn’t mean the journey is over. The risk of relapse remains high, leaving families like ours living with uncertainty.
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<div>Following frontline treatment, Florence was due to begin DFMO (difluoromethylornithine), a maintenance treatment that aims to help reduce the risk of relapse. DFMO is not currently part of standard NHS treatment, and families make different decisions after frontline therapy, including watch and wait or exploring relapse prevention options.
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<div>Sadly, just one week before Florence became eligible to start DFMO, the UK Expanded Access Programme closed. This meant there was no longer a route through that programme for newly eligible children like Florence to access the treatment.
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<div>We are now exploring access to DFMO through a privately funded Named Patient Programme, subject to approval from Birmingham Children’s Hospital. The estimated cost of treatment is around £100,000 over two years.
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<div>Thanks to the extraordinary generosity of our family, friends and local community, we have already raised almost half of this amount through our own fundraising. This campaign, in partnership with The Azaylia Foundation, aims to help us raise the remaining funds needed to give Florence the opportunity to access this treatment.
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<div>We know DFMO cannot guarantee that Florence’s cancer will never return. Sadly, no treatment can offer that certainty. Some children never relapse after treatment, while others sadly do, and there is currently no way of knowing which path Florence will take.
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<div>But after everything she has endured, we want to know that we have explored every possible option available to her. DFMO represents hope, and the chance to do everything we can to support Florence’s future.
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<div>Every donation, no matter its size, brings us one step closer to that goal.
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<div>Whether you choose to donate, share our campaign or simply help raise awareness, your kindness and generosity mean more to our family than words can ever express.
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<div>With love and gratitude,
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<div>Anna, Dom &amp; Florence (Florie) xx
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Anonymous

Help Florence access DFMO to reduce the risk of relapse

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Help Florence access DFMO to reduce the risk of relapse

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