<div><strong>Fighting for Debbie: Funding Her Personalised Life-Saving Treatment</strong>
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<div>Dear Friends, Family, and Supporters,
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<div>Five years ago, our beloved Debbie faced Stage 4 Hodgkin’s Lymphoma with incredible courage and won. We thought that dark chapter was behind us. Tragically, life has dealt Debbie another devastating blow completely unrelated to her past illness. At just 44 years old, Debbie has been diagnosed with a WHO Grade 4 Glioblastoma — an aggressive brain tumor.
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<div><strong>Urgent Update: Our New Goal &amp; Crucial Deadline</strong>
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<div>The medical facility in Germany requires the first full year of Dendritic Cell Therapy, along with the highly complex cellular logistics, to be paid in full, upfront.
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<div>Because of this rigid protocol, we do not have months to raise these funds incrementally. We must secure her first-year clinical costs immediately to ensure her living tumor tissue can be processed.
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<div>To cover her upfront medical bills abroad, past out-of-pocket structural adaptations, and immediate clinical support, we have launched a new, short-term, explicit target: <strong>Our Fundraising Goal is €120,000.</strong>
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<div><strong>The Medical Reality &amp; A Ray of Hope</strong>
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<div>Debbie underwent major brain surgery to remove the tumor. Her recent pathology reports outline a complex molecular diagnosis: Glioblastoma IDH Wildtype with an FGFR3::TACC3 fusion. While this is a serious and aggressive tumor, her specific genetic makeup reveals two crucial pillars of hope:
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<li><strong>The</strong> <strong>FGFR3::TACC3 Fusion:</strong> This rare driver alteration means her tumor has a specific molecular target that is potentially treatable with advanced, targeted therapies. Per her medical team, this specific fusion is associated with slightly longer survival rates.
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<li><strong>MGMT Promoter Methylation:</strong> Her supplementary tests show her tumor is MGMT Methylated (17%). This is a highly favorable prognostic factor indicating her cancer is statistically much more responsive to standard chemotherapy agents.
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<div>Because <strong>the standard Irish health system has no avenues for personalised vaccines</strong>, we must look abroad to save her life. We are coordinating specialised Dendritic Cell Therapy in Cologne, Germany. Doctors will use Debbie’s own preserved tumor tissue to create a personalised vaccine designed to train her immune system to aggressively target and destroy any remaining cancer cells.
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<div><strong>The Upfront Cost Breakdown</strong>
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<div>To get Debbie to Germany and maintain her care at home, we face the following costs plus travel and accommodation expenses:
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<div><strong>Debbie’s Timeline: A Crucial Roadmap</strong>
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<div>Debbie’s timeline is intense, and the windows to act are tight. Your support directly funds these exact milestones:
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<li><strong>21 May – 02 July 2026:</strong> Combined Radiation &amp; Oral Chemotherapy (Standard Care)
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<li><strong>27 Jul 2026 – 03 Feb 2027: </strong>6-Month Intensive Chemotherapy Block + Monthly visits to Cologne for Treatment.
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<div>Debbie has spent her whole life standing up for others, spreading humour in dark moments, and ensuring no one faces hardship alone. Now, she needs us to stand up for her.
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<div>Please donate if you can, share her story with your network, and keep Debbie in your thoughts. Thank you from the bottom of our hearts for helping us fight for her life.
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Ciara Brennan

Cormac Sheehan

Anonymous

Clara O Neill

Jason Douglas

Uma Talluri ferrer

Nat Stevens

Roberta Carroll

Michelle Cogan

FootballPlus Iago

ANNETTE HANLEY

Aisling O’Callaghan

Christoph Winterbach

Alice Burke

Noreen Power

Shell Cogan

Michael Deegan

Help Debbie Get the Treatment That Could Save Her Life

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Help Debbie Get the Treatment That Could Save Her Life

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