<div>Ten years ago, Miles and I completed a 200 mile walk from Eastbourne to Winchester and back. In 2016, it took us 16 days to complete the challenge. This year, marking the tenth anniversary of that journey, we hope to complete the same route in just 12 days.
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<div>Our original walk took place before Charlotte's BAG was established. Having lost Charlotte only a few months earlier, in February 2016, we felt we had to do something to raise awareness of brain tumours and honour her memory. That walk became the beginning of our commitment to supporting others affected by this devastating disease, and we're proud to be taking on the challenge once again.
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<div>Every donation helps fund research through Charlotte's BAG, where 100% of donations go directly to brain tumour research in Charlotte's Lab, King's College London.
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<div>We are a self funding charity. No overheads, salaries, merchandise etc.
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<div>Together, we continue to walk in Charlotte's memory and help fund vital brain tumour research through Charlotte's Lab at King's College London.
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<div>Every mile has a purpose.
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<div>Charlotte had lots in common with many teenage girls. She loved fashion, make-up, music and cats, and planned to go to college to study beauty therapy. She believed passionately in justice and fairness, and that kindness was an essential part of life. She was beautiful in every sense of the word, and loving and beloved.
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<div>Her world, and that of her family, fell apart in July 2013, when after suffering headaches for four months she was diagnosed with a grade 3 anaplastic astrocytoma with spinal diffusion. Over the 951 days the astrocytoma developed into a deadly grade 4 glioblastoma.
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<div>Despite this shattering diagnosis, Charlotte began to vlog via YouTube, talking to other young people about her experiences of life with cancer and living life to the full, despite her condition. Her voice has reached out to nearly 28 million people worldwide. Charlotte continued to vlog almost until the very end of her life, sharing conversations that were heartwarming, funny, emotional, poignant, and at times deeply sad. Today, Alex and Miles (Charlotte’s mother and Charlotte’s brother) continue to keep her channel alive as a lasting resource for young cancer patients and their families.
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<div>Below is how donations have been spent
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<div>Written by Barnaby - Consultant Clinical Scientist Charlotte's LAB
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<div>Support from Charlotte's BAG charity has enabled the laboratory at Kings College Hospital to purchase a high specification computer, which enables data to be processed in real time, as it is generated by the sequencer. This has already made a real difference to the speed at which we can diagnose brain tumour samples. Cutting-edge DNA sequencing technology combined with this computer power have reduced the time it takes to make a diagnosis from 21 days down to 2 hours. In some cases, the tumour diagnosis can be fed back to the surgeon whilst the patient is still under anaesthetic. This allows the surgeon to tailor surgery according to the tumour type, resulting in improved surgical outcomes for patients. Tumour DNA sequencing continues in all cases for 24 hours. This extended sequence is allowing the laboratory to collect information on other genetic regions which inform treatment and prognosis. All information is then available to the clinical teams ready for their first patient review meeting. When the clinical teams have all the information they can make better decisions for patient care. Now the computer specification has proven to be effective; the laboratory needs a second computer, to allow it to offer a clinical service. This will allow more samples to be sequenced at the same time and should provide contingency should any issues arise with the original sequencer and computer. The service at Kings College Hospital could also be offered to other hospitals in the region. By expanding testing capacity in this way, CBAG’s generosity will continue to have a direct impact on patients and families, supporting faster diagnoses, more efficient workflows, and improved care at a time when every moment matters. The impact of CBAG's investment has also been shared nationally and a programme is being compiled to ensure all surgical centres in England have access to this type of technology.
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<div>Every step is for those affected by brain tumours.
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<div>Every mile is in memory of Charlotte.
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Charlotte Tottman

Emma Jones

Hebe Sutton

Catriona Lane

Theresa Brosnan

Sarah Hunt

Mary Redfern

Olivia Field

Anonymous

Eileen brencher

Debra Evans

Shari Wind

Darren Halsey

Jennifer Giblin

Jacqueline walker

Harry Roberts

Dorothy Snowdon

Eddie Armitage

Carol Evans

200 Miles - 12 Days for Brain Tumour Research at KCH London

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