<div>I am organizing this fundraiser on behalf of my sister Christine and her husband Ed. Their almost-3-year-old daughter, my niece Adeline, has an extremely rare genetic disorder called Constitutional Mismatch Repair Deficiency Syndrome (CMMRD). Please take a minute to read about it <a href="https://medlineplus.gov/genetics/condition/constitutional-mismatch-repair-deficiency-syndrome/" target="_blank" rel="noreferrer noopener">here</a>. CMMRD is a condition that greatly increases Adeline’s chance of developing tumors in childhood leading to brain cancer, cancers of the blood, endometrial cancers, gastrointestinal cancers, and more. Almost all people with CMMRD syndrome develop cancer, often multiple times, before age 18. There is no cure.
</div>
<div><br />
</div>
<div>On April 30, 2021, an MRI revealed that Adeline has a 2cm mass on her brain on the temporal/parietal lobe border. It was also uncovered that there are additional abnormalities on her brain that the oncologists believe could become tumors in the future. A meeting at the Children's Hospital of Philadelphia on May 20th confirmed the need for surgery as well as the need for additional surveillance of the abnormalities. Once the tumor is removed, there will be a pathology report with a recommendation for potential treatment options. This may involve chemotherapy, radiation, and/or immunotherapy, depending on how aggressive the tumor is.  
</div>
<div><br />
</div>
<div>The surgery is scheduled for June 15, 2021, two days before Adeline’s third birthday. She will be hospitalized for up to four days after her brain surgery. Adeline’s parents, Christine and Ed, will be booking a hotel nearby so that they can be with Adeline 24/7 during this time.
</div>
<div><br />
</div>
<div>Their journey does not end post-surgery. In accordance with a strict and invasive surveillance schedule as advised by the AACR (American Association for Cancer Research), Adeline will need MRIs, colonoscopies, endoscopies, ultrasounds, CAT scans, blood tests, doctor visits, and more every 3-6 months for the rest of her life. Some MRIs on the brain and spine could last 2.5 hours or longer and require heavy sedation. Most individuals have a handful of colonoscopies in their lifetime. By the time Adeline is ten, she will have had over a dozen.
</div>
<div><br />
</div>
<div>CMMRD is extremely rare (less than 500 cases known in medical literature), which means that Christine and Ed will need to visit specialized hospitals all over the world to meet the few experts in this field in order to give Adeline the best possible quality of life. This ranges from hospitals in New Jersey, New York, Philadelphia, Boston, Toronto, and more. Transportation and lodging are costly and typically are not covered by insurance.
</div>
<div><br />
</div>
<div>Adeline faces lifelong invasive testing. The probability of her having multiple cancers over the course of her lifetime is extremely high. Christine and Ed, as parents, will be dealing with feelings of sadness, anxiety, depression, hopelessness, anger, and confusion for years to come. They know they need to be strong and stay positive for Adeline's sake. They will be engaging with therapists and support groups with other parents of children with cancer and rare diseases, many of which are specialized, and add on additional expenses.
</div>
<div><br />
</div>
<div>Here is what your donation would go to: 
</div>
<div><br />
</div>
<div>-- Travel to various doctors, researchers, specialists in this field, who may be located anywhere in the world, given the extreme rarity of this syndrome
</div>
<div>-- Lodging for any related travel
</div>
<div>-- Unforeseen / Out of Network medical expenses
</div>
<div>-- Potential gene therapy trials, not covered by insurance, as they become available
</div>
<div>-- Therapists / Consultations with grief counselors/psychologists for the parents and Adeline
</div>
<div>-- Supplies directly related to Adeline not covered by insurance (meds, bandages, etc)
</div>
<div><br />
</div>
<div>I will share updates of how your donations have helped and on how sweet Adeline is progressing as I can. Thank you for reading and helping, and thank you -- from the bottom of our hearts -- for your continued support during this incredibly difficult time.
</div>

Carmen M. Flores

Fior Paredes

Anonymous

Giannakas Michalis

Oby Nwankwo

Nan Rosenblatt

Christine Christensen

Michael Downes

lisa baum

Barbara Doyle

Debbie Smith

Rebecca Leaf

Monica Boyle

Rohan Panchamia

Yazmin Fuentes

Help Adeline Fight a Rare Genetic Cancer Syndrome

platform

Platform is iOS

Android

Adyen Google Pay Development Audience

$opt_dummy_attribute

English only

Deprecate Stripe Legacy

dyn_template_ids

Adyen V6 Bene Transfer & MyMoney Campaign Organizers - test01

Bene transfer V6 and AdyenV6MyMoney Campaign Organizers - production

OneTrust next-app audience

fundCountryCode

NextDoor Share Option Users

Fundraisers with Reactions feature capability

fundCurrencyCode

US + Non-charity COs Only

locale

fund country is US and user language is English

personId

comms-internal-person-ids

Enhanced Story Experience Users

Suggested Goal Experience Users

user language is English and fund country: US, AU, DK, FI, IE, NO, SE, CA, GB; 

Poster share - new funds eligible (newest 9/18)

Streaming widgets beta user

paymentProcessor

3DS payment method

user language is English and fundCountry: US, AU, DK, FI, IE, NO, SE, CA, GB; 

currencyCode

Money Box Donation List Prompt Experiment Audience

GoFundMe Employees

ipAddress

Mark Rieth IP Address

Version 9.2.0 and above

Fund is in English speaking country

desktop

Android v12.11.0 and above

Platform is Android

paymentMethodType

checkoutType

Payment method type group to be vaulted on success

admin pr kit prod

EUR Donation Upsell

Share Text generation Skip Fundraiser

(prod) new funds eligible for amp12 (UGC gallery)

fintrac_cad_idv_form_v2 audience

paymentProcessorAccountId

fallback mode accounts

proCampaignId

p2p legacy startfundraising page

AMP24 New Funds Only PROD (DO NOT MODIFY)

Eligible for Profile Share Badge

countryCode

charityId

UKCharities

Federated Search Internal Testing

route.pathname community

US Donation Upsell audience 

Auto Thanks Feature Audience

Supporter Comments Eligible Funds

International Only

fundId

braze fundraiser group 

Payment Identity Transfers ATO Risk Check (Targeted) - Production

Fundraiser Saved Payment Method Rate Limit Bypass (Production)

leaderboard-partner-id-audience-givepanel

Version 9.2.1 and above

AUD Donation Upsell audience

fundraiserCountryCode is US/EN

Active Fundraiser - Smart Default Cadence

DAF Internal

Vault on success card payment method

Platform is iOS v11.0.0 and above

Desktop users

Person ids

United States (US) users

allow yuno fundraisers for test

Mexico country code

Posters INTL

NPO Profile Opted-In

iOS at or above 12.4.0

non-US recurring donors

Canada Campaign Owner Group

Fundraiser Without Meta Link

Scheduler payment tester gorup

charityCommunityId

Charities allow to be claimed unclaimed (PRD)

Canada (CA) users

UC Tipping v20250115 International

pymk_production_xplr_fe_team

Android at or above 12.2.0

Profile photo entry point audience

smart goals (fundraiser/manage) on test01

Activity Tracking v1 Beta Testing

start gfm intl allowed locales

Platform is iOS v11.2.0 and above

NPO upsell education category

unclaimed charities

prod_ach_audience

AI Chatbot Audience

amp13 only new funds (prod) (anyword auto)

UC Flow Enabled (Prod)

Payment Identity Beneficiary Verification - Production

shared notification bell audience

Custom users

ach frontend audience

Android v11.0.0 and above

Users Receiving Payments Paused Notifications

smart goals test01

Manage Coach - US English Organizers Only + new funds only

Team EGG - IP Address list

NPO recommendations prod

Fundraiser Without Instagram Deep Link

Native 11.4.0 and above

UC Tipping v20250107

Users Receiving Braze KYC Validation Failed

ai_title_page

anyword

openai

control

manual_entry

userEmail

template_id

userId

fundUrl

isCharityCo

email

appVersion

shouldBucketIntoExperiment

isEligibleForProfileBadge

partnerId

donationCadence

isActiveFundraiser

isPartner

isMobile

npoProfileOptIn

fundIsLinkedWithMeta

hasSessionDonation

categoryGroup

isCampaignOwner

fundHasInstagramDeepLink

Native 11.3.0 and above

Native 11.4.0 and higher

New funds eligible - Video Sharing (PROD)

GB Donation Upsell audience 

Auto Thanks V3 Rollout Audience

Thank you V3 testing whitelist

isRecurringFriendly

Is Recurring Friendly

Excluded funds - Video Sharing

NPO upsell animals category

NPO upsell disaster relief category

Logged In Users

CH Donation Upsell audience

Android v10.6.0 and above

NPO upsell essential needs category

NPO upsell medical category

userCurrencyCode

Localized Currency

NPO upsell cancer category

v11.5.0 and above

testAudience

pathname

Survicate

appVersion is at or above 12.8.0

Non-charity fund

isChallengeFundraiser

challenge-fundraisers

Payment Identity Launch Verification - Production

New funds eligible - Posters v2

CAD Donation Upsell Audience

Braze Email Tester

NPO Profile Opted-Out

iOS App Version

hasKnownDonors

PYMK has donors

iOS v12.3.0 and above

Help Adeline Fight a Rare Genetic Cancer Syndrome

Still $49,572 to go. Help us build momentum.