Helping to find the cure for Lymes
Specifics of the Project Seeking Funding for:
Develop/Expand a pediatric Lyme disease biobank at a Northeast based Children’s Hospital with existing clinical study sites and over 1,000 children enrolled.
Of the more than 300,000 new cases of Lyme disease diagnosed each year, up to half occur in children. Currently available Lyme disease diagnostics have well-recognized limitations that can lead to both under and over diagnosis of Lyme disease and may miss important tick-borne coinfections. Until now, few children have been included in studies that evaluated new approaches to Lyme disease diagnosis.
The situation is urgent because every day, 200+ kids are diagnosed with Lyme disease and many of them become so ill, that their childhood is taken away from them: loss of cognizant skills; memory issues; debilitating fatigue; migraine headaches; severe arthritic type conditions; fibromyalgia type pain; and the list goes on. We need to save lives not from death, but equally as insidious, save lives from a life unable to live normally.
In 2015, our key investigator founded a Lyme Disease pediatric research network with an associated biobank. Global Lyme Alliance’s support will allow the ongoing enrollment of children undergoing evaluation for Lyme disease, increasing the clinical and geographic diversity.
The Global Lyme Alliance needs to raise sufficient funding to support a Pediatric Multi-Center Lyme Disease Research Network with Biosample Collection. The dollars will be used to initiate a specific study to better understand how Lyme disease infiltrates the immune system of children and whether or not that would require specific treatment protocol different than adults, which we believe it might.
We will also explore the proportion of children with Lyme disease that have evidence of other tick-borne coinfections. Our ultimate goal is facilitating the development of novel diagnostics for Lyme disease and other related coinfections with high accuracy for children.
The work will be conducted with two specific goals:
Goal I: augment the number of children undergoing evaluation for Lyme disease recruited at one of the participating sites in order to increase the clinical and geographic diversity.
Goal II: explore the frequency of other tick-borne infections in children with Lyme disease. The resulting pediatric Biobank will provide a valuable resource to develop and further refine candidate assays, ultimately aimed at optimizing the diagnosis of acute Lyme disease as well as tick-borne coinfections in children.
$150,000 Primary Investigator/Researcher
$125,000 Biobank Development and Management
$ 75,000 Sample collection and data processing
$ 75,000 Post Doctoral Fellow Researcher
$ 50,000 Research Assistant
$ 25,000 Supplies and Materials
** With every donation of $20.00 or more we will contact you via email to extend our graditude by sending you a limited edition, numbered coin from our sponsor partners-- United Treasure Hunt . The coins can be redeemed through a interactive, fun incentive program where additional proceeds will be donated to GLA from your participation.
The funds will help us achieve our goals by advancing our mission of trying to eradicate Lyme disease through innovative research. Studies like the one we are proposing to fund, will enable researchers to better understand the uniqueness of Lyme disease in children and perhaps help identify factors, biomarkers, or triggers within children that we don’t see adults and begin to provide answers toward improved treatment options beyond just antibiotics. It will also help provide hope to the families struggling to combat the disease.